Retail Businesses For Sale in South Carolina

Start-upOwn a Global Brand – Leguano® Franchise, 250+ Stores in 21 Countries

Leguano® is a German company with manufacturing based in Germany, recognized as the country’s leading barefoot footwear brand with more than 250 branded stores worldwide. The company combines...

$30,000

Start-upOpen an eBike Shop - 4 Revenue Streams - No Royalties

BUSINESS OPPORTUNITY OVERVIEW The eBike Shop presents an exceptional entry point into the rapidly expanding electric bike industry. This comprehensive business model combines sales, service, rentals,...

$19,000

Start-upWomen’s Boutique Franchise Opportunity.

Ella Blu presents an exceptional franchise opportunity in the upscale women's boutique market. Founded by Courtney Lyons, who has successfully owned and operated her boutique for over 22 years, this...

$50,000

Start-upTurn Key Packing & Shipping Stores, available starting at $75,000

Start your own profitable shipping and logistics business—affordably. At Qwik Pack & Ship, our mission is simple: empower entrepreneurs to own a proven, in-demand business without franchise fees or...

$37,500

Start-upProfitable Cabinet Dealership – $250k+ Potential, No Royalties

Are you a successful sales leader, corporate professional, or veteran who has hit an income ceiling? Are you tired of building someone else's dream and ready to invest in a real, tangible asset for...

$250,000

Sales $1.89 Million. Cash Flow $265K. SC Low Country Resort Area

South Carolina

Profitable, Destination Liquor Store Operation. Very Established Business with 17 Year Tenure in this beautiful community. This Business continues to grow due to South Carolina being the fastest...

$697,000

Cash Flow: $265,000

FranchisePlato's Closet

Available Nationwide

Be a part of the #1 rated franchise in its category by Entrepreneur Magazine.

$90,000

$90,000

Vending business and location

Greenville, SC

ESTABLISHED ICE AND WATER VENDING BUSINESS - GREENVILLE, SC This turnkey ice and water vending operation features the premium Everest VX ice vending machine, recognized for its superior reliability...

$40,000

Cash Flow: $26,000

Boutique Store, Designer Furniture, Home Decor and Unique Gifts

Horry County, SC

Charming Boutique in Premier Shopping Destination: High Margins & Growth Potential! Nestled in an upscale, high-traffic shopping center, this established boutique is a go-to destination for discerning...

$239,000

Cash Flow: $81,255

Liquor Store for sale in Charleston, SC area

North Charleston, SC

Established and operating liquor store for sale in Dorchester County, South Carolina. The business is currently open and generating consistent monthly sales, with opportunity for further growth....

$70,000

Meticulously Curated Whole Food Plant-Based Nutrition Flagship

South Carolina

This is not a food business. It is a brand — with proprietary recipes, a trademarked identity, a vetted supplier network, and a newly launched product line that hit the market to immediate demand....

$200,000

Established Multi-Service Medical Practice

Charleston, SC

Key Investment Highlights • Established, physician-led outpatient medical practice with more than 25 years of continuous operation in the Charleston market. • Diversified, integrated service platform...

$1,695,000

Cash Flow: $472,204

Antonio Williams

Keller Williams

Serving York County, SC

KW Commercial — Company Overview (Executive Summary) What it is: KW Commercial is the commercial real-estate community and business unit within Keller Williams Realty, LLC (KW), offering commercial brokerage services, industry training, technology, branding, and national/regional brokerage networks to commercial agents and teams. KW Commercial Parent company scale & standing: Keller Williams is the world’s largest real estate franchise by agent count and regularly ranks as the No. 1 U.S. real estate franchise by agent count, transaction sides and sales volume. This broad residential franchise footprint provides scale, referral pathways, and brand recognition that support KW Commercial’s reach. Keller Williams Core Offerings & Capabilities Brokerage services: Commercial listing, acquisition, leasing, investment sales and landlord/tenant representation across asset classes (retail, office, industrial, land, multi-family, hospitality). KW Commercial Membership & network: KW Commercial operates as a membership community for commercial brokers (membership includes training, networking, marketing templates, deal-flow platforms and access to the KW agent network). Membership features and resources are centralized through KW Commercial platforms and events. Keller Williams Communities Training & events: Dedicated commercial training, annual summits and masterclasses aimed at scaling broker practices and deal execution. Keller Williams Communities Technology & platforms: Access to KW technology stack and third-party integrations for lead generation, CRM, and listings (properties database and agent directories on kwcommercial.com). KW Commercial Scale, Footprint & Financial Signals Agent & office scale (parent company): Keller Williams has the agent scale and market center distribution that creates cross-referral opportunities for commercial listings and buyers; KW parent press releases cite the company’s top-rank franchise position and material agent counts

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$750K Revenue Upstate Boutique $150K SDE

South Carolina

Step into ownership of an elegantly established ladies’ clothing boutique generating over $750,000 in annual revenue with $150,000 in profit. The curated, ready-to-sell inventory is additional @...

$370,000

Cash Flow: $154,054

Liquor Store. Very Busy Area

Greenville County, SC

In South Carolinas busiest street...

$400,000

Huge Price Reduction - Great C and Liquor Store only $70k!!!

Enoree, SC

This is a prime location with strong growth potential. Rare opportunity to own both a convenience store and liquor store with low overhead and great traffic. Gross sales $600,000+. Just under $85,000...

$70,000

Cash Flow: $100,000

Established Luxury Retail Store – Turnkey, Profitable, Prime Location

Charleston, SC

This established Charleston luxury retail store has been a trusted destination for home décor, linens, gifts, and bridal registry services for generations. The store features extensive luxury bedding...

$375,000

Cash Flow: $179,844

500+ Review Ice Cream Shop w/ Comics, Cards & Boba

Hilton Head Island, SC

Captain Jax Comic Shop is a well-established comic book and pop culture retail store located on Hilton Head Island, South Carolina. This turnkey business offers a unique opportunity to acquire a...

$225,000

Cash Flow: $200,000

FranchiseClothes Mentor®

Available in South Carolina

If you have been feeling the need for a professional change that offers flexibility, growth potential, and personal fulfillment, Clothes Mentor franchise ownership might be the path you have been searching for. The resale industry is booming, and franchising has real advantages, but the best part is the process is already nailed down for you.

$100,000

$100,000

Vape Store - Owner Operated - Inventory Included - Will Train!

Greenville County, SC

Bring All Offers! Seller Highly Motivated, looking to Relocate ASAP. Price of $150,000 includes the Inventory. Seller is willing to negotiate the price. Owner Operated Vape and Tobacco Business on one...

$150,000

Cash Flow: $93,421

Turn Key & Cash Flowing Vending Route w/ Latest Vending Technology!

Charleston, SC

ESTABLISHED VENDING MACHINE ROUTE - CHARLESTON METRO AREA This turnkey vending machine operation represents a fully established business opportunity in the Charleston metropolitan region, specifically...

$155,000

Cash Flow: $40,000

Hot Tub Store for Sale in South Carolina

Charleston County, SC

LISTING ID # 36421 Discover this well-established retail store specializing in hot tubs, swim spas, and saunas. While the business has been established for the last 8 years, the current owner has run...

$825,000

Cash Flow: $210,000

$130k Net Profit: Liquor Store/C-Store Combo

Anderson County, SC

Deal Structure: Store and Inventory Sold Separately - Store Price $275,000 with $75,000 Seller Note at 8% - Inventory is estimated at $200,000 for the Liquor Store and C-Store combined. Total Cost is...

$275,000

Cash Flow: $138,623

SC Bike Shop for Sale

Greenville County, SC

Established South Carolina Bike Shop - Turnkey Operation in Growing Market This well-established bicycle retail, service, and rental business has been serving Greenville County since 2014, generating...

$450,000

EBITDA: $60,000

High Margin CBD/Vape Store for Sale with no Competition

Beaufort, SC

Established CBD/Vape Store - Prime Beaufort Location This thriving smoke shop presents an exceptional opportunity for an entrepreneur seeking a profitable retail business in Beaufort, SC. Operating...

$150,000

Southern Charm Bridal Shop & Tuxedo Rentals

Hilton Head Island, SC

Transform Your Entrepreneurial Dreams Into Wedding Magic Step into immediate profitability with this turnkey bridal and formalwear empire that delivers everything you need to dominate the lucrative...

$230,000

EBITDA: $85,156

Well-established Coastal Florist for Sale

Georgetown County, SC

************NOT SBA ELIGIBLE / CASH HEAVY / ALL NUMBERS CAN BE PROVED********** This represents a rare opportunity to acquire a highly profitable, full-service floral retailer and design studio...

$100,000

Cash Flow: $89,294

Charleston Vape Store Monthly Sales $60k+ and Inventory Included

Charleston, SC

This Vape Store will go quickly. If you want it, come and get it. The Vape Industry is extremely Popular and is showing no signs of slowing down. This store is located in a Busy Charleston Area and...

$600,000

Outdoor & Casual Clothing Retailer

South Carolina

The Company is a reputable retail business with a loyal customer base, extensive inventory, and a high-visibility South Carolina location. The store specializes in outdoor and casual apparel,...

$1,990,000

Cash Flow: $503,431

FranchiseGet In Shape For Women

Available in South Carolina

Get In Shape For Women is an upscale, boutique fitness concept, where 1 trainer works with up to 8 women at a time, for 55 minutes, for as little as $20 per session, delivering the most compelling results in the shortest amount of time. We combine weight training, cardio, nutrition, and accountability for a complete solution.

$50,000

$50,000

Well Established Scandinavian Modern Style Home Furniture Store

Charleston, SC

WELL ESTABLISHED SCANDINAVIAN MODERN FURNITURE STORE - CHARLESTON, SC This turnkey furniture and home decor business represents a rare opportunity to acquire a professionally branded, well-established...

$899,000

Cash Flow: $185,000

Hemp Healthcare Business with Greenhouse & eCommerce

Columbia, SC

Overview Step into ownership of a thriving, fourth-generation hemp business that blends tradition with innovation. This Hemp Company has a trusted name in South Carolina, known for its commitment to...

$180,700

Confidential Liquor Store for Sale: Bamberg County, SC

Bamberg County, SC

A unique opportunity awaits a motivated buyer to acquire a liquor store in a quiet, picturesque town in the heart of the South Carolina Lowcountry. The business is a staple of the community and the...

$99,000

Cash Flow: $15,573

Upscale Mobile Custom Suits/Blazers Biz w/70% Net Profits!

Greenville, SC

Imagine running your own upscale mobile tailoring business where you're bringing premium custom clothing directly to high-end clients in the thriving Greenville-Spartanburg area. This isn't just any...

$54,000

Flooring Sales and Installation $1.4M Sales | Western Horry County

Horry County, SC

This legacy business had a fantastic year in 2025 and continues to generate solid sales and earnings with experienced staff and growing trends in place. BUSINESS IS UP!! Pushing $1.4M in sales last...

$329,000

Cash Flow: $180,000

FranchiseTechy

Available in South Carolina

Exciting Opportunity Alert! No experience needed! Join the TECHY electronics repair franchise and kickstart your entrepreneurial journey hassle-free. Techy, partnered with retail giant, Walmart, leads the electronic repairs and sales industry. Benefit from professional training and support to ensure your success. Plus, with our unique TECHY CAFE concept, combine the power of electronics and coffee in one dynamic location! Join our global family now located in 27 States and 11 Countries - inquire now!

$45,000

$45,000

Turnkey Opportunity: Thriving Liquor Store

Beaufort County, SC

The offering is a locally owned and operated retail liquor store that has been serving the Bluffton community for over 15 years. Known for its wide selection of liquor and carefully curated wine...

$123,900

Cash Flow: $66,000

Specialty Home Furnishing Shop Offering Unique Opportunity

Mount Pleasant, SC

We are offering a unique opportunity to take ownership of a one-of-a-kind specialty furniture retailer with a strong 25+ year presence in the Charleston, SC market. Known for its extensive inventory...

$60,000

Cash Flow: $71,426

Charleston, SC- Automotive Repair Franchise

Charleston, SC

Simple, repeatable operations that generate robust cash flow, boasting an impressive 70%+ repeat customer rate. Situated in a prime retail-dense trade area, this franchise is strategically positioned...

$1,500,000

Cash Flow: $600,000

Start-upHigh Margin E-Cig/Nicotine & Custom Vending Machines!

Looking for your next side hustle? Sunstate Vending is a U.S. based premium vending provider looking to break the barrier of entry into entrepreneurship. We specialize in high end software driven...

$15,000

Seafood Market / Fish Market for Sale – South Carolina

$15,000

South Carolina

Large Christian bookstore in business for over 40 years. Excellent reputation for quality products and customer service. The store is open six days per week selling Christian books, bibles, music,...

$730,000

Cash Flow: $162,954

Tonya Morgan

Mosaic Advisory Partners

Serving Charleston County, SC

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Columbia, SC

This is a highly profitable seafood market located in South Carolina, known for its exceptionally strong sales and impressive net income. The business has built a loyal and consistent customer base...

$800,000

Lexington, SC - Upscale Convenience Store, Fuel and Liquor Store

Lexington, SC

High-Volume Convenience Store, Gas Station, Deli & Liquor Store – Lexington, SC (Lexington County) Exceptional opportunity to acquire a well-established, upscale branded fuel station located in the...

$599,000

Only for those with a passion for the outdoors.

Beaufort County, SC

A 16-year-old outdoor lifestyle business with deep roots in the Lowcountry community with a 3-year average revenue of $681,296, a recognizable name, an established customer base, and a marketing...

$180,000

Cash Flow: $94,000

Downtown Boutique with Rave Reviews

Beaufort, SC

Step into one of Beaufort's most beloved retail experiences. This charming clothing boutique has built a devoted following in the heart of Downtown Beaufort — known as much for its warm, personal...

$85,000

Cash Flow: $37,000

Seasonal beachside shoppe, small but mighty

Beaufort County, SC

This is a rare one. A multi-revenue retail and convenience store operating as the only commercial outlet on a private Lowcountry gated community — serving vacationing families, seasonal residents, and...

$90,000

Cash Flow: $36,000

FranchiseOnce Upon A Child

Available Nationwide

Once Upon A Child buys and sells gently used and new children’s clothing, toys, equipment and more! With over 415 stores open in North America we are the nations largest chain of children’s resale stores.

$90,000

SG 11507 South Carolina Columbia Main Branded Gas Station with Propert

REAL ESTATE INCLUDED

Richland County, SC

$2,200,000 Plus Inventory for South Carolina, Columbia, Main Branded Gas Station C- Store Business and Property. $80,000 average - $85,000 monthly merchandise sales with higher margins. 20,000 average...

$2,200,000

Cash Flow: $320,000

REAL ESTATE INCLUDED

Lawn and Garden Equipment Dealer

Charleston County, SC

Full-service lawn, garden equipment dealer, trailer and tractor dealer. Original owner of 36 years is ready to retire presenting a terrific opportunity for the next owner. Along with full product...

$799,000

Cash Flow: $265,504

Summerville, SC

This Company is a multi-location provider offering integrated weight management, aesthetic, and hormone therapy services through both in-person and telehealth platforms. Positioned as a “one-stop...

$385,000

Cash Flow: $66,890

Healthy Vending Route serving Myrtle Beach, SC - Lucrative

Myrtle Beach, SC

Own a turnkey, scalable business in the heart of the Grand Strand - Greater Myrtle Beach. This semi-passive model is built for efficiency—each machine requires only about one hour of total weekly...

$150,000

Cash Flow: $173,000

Established Charleston Artisan Gallery with Strong Local Brand

Charleston, SC

Established Charleston artisan gallery in prime location with curated vendor relationships, strong visual merchandising, and owner-operator upside. This long-established artisan gallery and gift...

$450,000

Cash Flow: $59,000

FranchiseBig Frog Custom T-Shirts & More

Available in South Carolina

Tired of the corporate grind? Consider becoming part of a booming custom t-shirt and apparel industry that’s expected to more than double by 2030, with Big Frog Franchise. Own a lucrative, fulfilling, and FUN retail business with multiple revenue streams, minimal staffing needs, a 62.5% average gross profit margin, and low investment and inventory costs.

$250,000