Businesses For Sale in Monroe County, FL

Available in Florida

Build a scalable, year-round business. We Take The Stress Out Of Running Your Business! Ledgers offers tax, payroll, compliance, and business advisory services to small businesses and individuals desiring a full-service provider through its franchised firms in various locations.

$48,000

Deep Sea Fishing Charter Business

Key West, FL

For Sale: Turnkey Deep Sea Fishing Charter Business in Key West, FL – Sea Clusion Own a piece of paradise and step into a fully operational, highly rated deep-sea fishing charter business based in...

$100,000

Cash Flow: $15,500

Profitable Key West Charter Business with Loyal Clientele

Key West, FL

Profitable Key West Charter Business with Loyal Clientele Turnkey Operation Includes the Boat, Equipment & Online Bookings Established in 2021, this thriving charter boat business operates from the...

$370,000

Cash Flow: $78,000

Trusted Residential and Commercial Construction Company

Monroe County, FL

One of the most established and trusted names in residential and commercial construction is ready for new owners to take it into its next era of profitability! Serving the Florida Keys and beyond with...

$500,000

Cash Flow: $166,858

Pet store & Supplies and Property 50 yrs of success! Amazing Location

REAL ESTATE INCLUDED

Key Largo, FL

Tropical Business Opportunity in Paradise! Are you ready to live the dream in the Florida Keys and own a thriving business? Here's your chance! The owners are willing to finance the property with a...

$2,500,000

Cash Flow: $91,588

REAL ESTATE INCLUDED

Florida Keys Waterfront Bar & Restaurant

REAL ESTATE INCLUDED

Islamorada, FL

Iconic Waterfront Restaurant & Bar For Sale Including Real Estate located in Islamorada Florida. Approx 8 acres of Real Estate including bay bottom. This property is located directly on the open...

$23,000,000

REAL ESTATE INCLUDED

Eric Marchand

MARCHAND REALTY LLC

Serving Monroe County, FL

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Rare Free-Standing Florida Keys Restaurant & Bar – Turnkey Asset Sale

Asset Sale

Key Largo, FL

Rare Free-Standing Upper Florida Keys Restaurant Opportunity Asset Sale | Long-Term Lease to Be Negotiated This offering represents a rare opportunity to acquire the assets of a fully built-out,...

$650,000

**Rare Monroe County Quota Liquor License now available**

Asset Sale

Monroe County, FL

Imagine the possibilities that await you with this rare Monroe County full quota liquor license - your gateway to owning a thriving hospitality business in one of the most sought-after markets. You...

$1,300,000

Restaurant with employee housing for sale

Real Estate Only

Islamorada, FL

Rare opportunity in downtown Islamorada. This property is on three quarter of an acre with six transient units,one market rate unit plus a commercial restaurant. Lots of options from a restaurant with...

$4,500,000

Prime Lower Keys Commercial Property For Sale

Waterfront Trophy Investment Property & Marina

Summerland Key, FL

Prime Lower Keys Commercial Property for sale on Ramrod Key. 3 Lots total 28,132 sf. or .65 acres with nearly 189' of frontage on Overseas Hwy aka Jimmy Buffett Memorial Hwy.!! Excellent visibility...

Not Disclosed

Real Estate Only

Tavernier, FL

Waterfront Trophy Investment Property & Marina located in the heart of Tavernier. Highly visible location with 250 ft. on Old Rd and Rt 1. Total of 4 parcels (Parcel ID #'s-00436050, 00436680,...

$7,900,000

Miracle Method Surface Refinishing

Available Nationwide

Average Annual Franchise Revenue: $1,355,173!* Join the #1 Surface Refinishing Brand, ranked by Entrepreneur Magazine!

$45,000

Key West Restaurant, Bar & Apartments – Multiple Income Streams

Prime Duval Street Building for Lease

Key West, FL

Imagine yourself operating a thriving restaurant and bar in the heart of Key West's legendary entertainment district! This incredible lease opportunity puts you just half a block from the famous Duval...

Not Disclosed

Lucrative Lower Keys Staging Business For Sale

Key West, FL

Prime Duval St. 2 story, free standing building For Lease on the 100 Block of Duval. Perfect for a Retailer or Restaurant/Bar looking for prominence with a Showcase location in the heart of Old Town...

Not Disclosed

Key West, FL

LUCRATIVE LOWER KEYS STAGING BUSINESS FOR SALE Established in 2020, this successful staging business has built an outstanding reputation throughout the Florida Keys, serving Realtors, homeowners, and...

$250,000

REDUCED:Charter Fishing Business for sale in Islamorada in the FL Keys

Islamorada, FL

PRICE reduced from $300k to $250k, and includes boat! Includes Vessel: Rigged and Ready 32 ft Regulator (2003) w/ Twin 300 HP Yamaha Motors Prime Location: Docked at the world famous robbie’s marina...

$250,000

Premier South Florida Transportation & Shuttle Service

Monroe County, FL

This is a highly reputable, fully authorized transportation and shuttle company serving the lucrative tourism and commuter corridor between major South Florida international airports and the Florida...

$1,300,000

Cash Flow: $363,288

Dons' Place Bar & Liquor Store

Key West, FL

Buy a Bar & Liquor Store in Key West! Dons' Place is the opportunity to purchase an Iconic and Landmark Indoor and Outdoor Bar & a Liquor Store with a Drive Through! This package is rarely available...

$3,500,000

Famous Key West Fishing Charter Business for Sale

Monroe County, FL

Seize a unique opportunity to acquire an established and reputable deep-sea fishing charter business in Key West, Florida, a globally renowned sportfishing destination. This is an exceptional chance...

$39,000

Cash Flow: $24,725

Profitable Bait & Tackle Shop for Sale | Islamorada, FL

Monroe County, FL

Bait & Tackle Shop – Islamorada Established in 2019, this profitable shop serves local anglers and tourists with live and frozen bait, premium tackle brands (NLBN, Nomad, Johnny Jigs), and is an...

$465,000

Cash Flow: $116,406

Pet Apparel & Specialty Pet Supply Store

Key West, FL

Blue Cat and Red Dog Too is a charming, turnkey pet boutique located at 291 S Front Street in Key West, positioned in one of the island’s most walkable, high?traffic retail corridors. The shop is...

$75,000

Cash Flow: $50,000

Boat Rental And Airbnb Business

Key West, FL

Turnkey boat charter and Airbnb business in Key West featuring a 42' Maxum cabin cruiser set up for short-term rental use, plus a 17' Angler (2023 Suzuki 140HP) and 22' Hurricane (Yamaha 150HP) for...

$299,000

EBITDA: $80,000

SYNERGY HomeCare

Available in Florida

The average annual gross sales for a SYNERGY HomeCare multi-territory franchise operation in business for over 1 year is $2,116,737. $2,116,737 is the average gross sales of 141 mult-territory businesses (478 territories) that have been in operation for all of 2025. 54 Businesses (38%) met or exceeded the average annual Gross Sales. There is no assurance, however, that you will do as well. See item 19 of our Franchise Disclosure Dcoument.

$50,000

Mobile Marine Service Business

Key Largo, FL

Mobile Marine Service Business offering Dock-side service in the Florida Keys This turn-key well established business has gained a solid client base with its fine reputation in the industry...

$450,000

Established Business with over half an acre of property on US 1

Key Largo, FL

Long-Established Bait & Tackle Store with room to expand on one of USA most traveled thoroughfares Overseas Highway in the Florida Keys Included with the Sale is this Prime Real Este location of over...

$2,990,000

Apparel & Home Goods Boutique in High-Traffic Key West Location

Monroe County, FL

This established boutique offers a curated selection of apparel, fabrics, accessories, and home-lifestyle goods in one of Key West’s highest-traffic retail corridors. The store benefits from...

$135,000

Cash Flow: $74,794

Florida Keys The UPS Store Franchise

Big Pine Key, FL

Be Your Own Boss with the Industry Leader The UPS Store network has more than 40 years of franchising experience. The UPS Store offers business opportunities that can make a difference in your...

$350,000

Transform Boats & Your Lifestyle – Custom Decking Business

Monroe County, FL

It’s time to be your own boss! Work-life balance, financial success, & the rewarding experience of helping customers transform their vessels into something they absolutely love can be yours with this...

$615,000

Cash Flow: $237,744

Spherion Staffing & Recruiting

Available Nationwide

Generate $6.9 million in annual revenue* with America’s premier staffing franchise. Ranked #122 overall on Entrepreneur’s Franchise 500 and a Franchise Business review Top Franchise. Grow your income while empowered by our vibrant, supportive corporate team and franchise community.

$250,000

Cash-Flowing Legal Practice – $400K+ Earnings, Systemized Operations

Key West, FL

STEP INTO IMMEDIATE PROFITABILITY with this turnkey criminal defense firm that delivers consistent seven-figure revenues and exceptional profit margins exceeding industry benchmarks. You'll acquire a...

$1,250,000

Cash Flow: $722,637

Crazy Deal in the Upper Fl. Keys / 5.6mill buys the Biz & Real Estate

Asset Sale

Monroe County, FL

For two decades, a visionary entrepreneur recognized the untapped potential of the Upper Florida Keys marine market and built what would become one of the region's most respected boat dealerships....

$5,600,000

World Famous Alabama Jacks

Real Estate Only

Key Largo, FL

Once-in-a-Lifetime Opportunity: Own the Iconic Alabama Jacks in Key Largo! Step into the legacy of one of the most celebrated waterfront establishments in the USA. This legendary bar and restaurant,...

$6,000,000

Prime Lower Keys Commercial Real Estate For Sale

Opportunity to lease a entire Self-Storage Facility

Cudjoe Key, FL

Prime Lower Keys Commercial Real Estate for sale. Excellent visibility and easy access from Overseas Hwy. Corner location at MM 21 and Blimp Rd. Total of 3 Parcels of Land. With the Submerged...

Not Disclosed